Scientific and Resource Library

Explore our curated library of materials to support and extend the EpiFundamentals content. Access latest research insights and download helpful assets to support your understanding of epithelial science. Remember to check back as the library will be updated regularly

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Explore this slide content to learn more about the role of epithelial cytokines in atopic march.

Slide deck outlining the different testing methods for airway hyperresponsiveness

Infographic summarising the important roles IL-25, IL-33, TSLP and mast cells play in allergic T2 and beyond T2 pathways

Slide deck describing the roles of airway inflammation, airway remodelling and structural changes in airway hyperresponsiveness

Watch this video to learn more about the inflammatory cascade that drives asthma pathogenesis and explore how epithelial cytokines initiate inflammation through their effects on various immune cells

Watch this video to learn more about the role of epithelial cytokines in asthma and their role in driving disease pathogenesis

Watch this video to learn more about the pathological changes that occur in the airways of people with asthma and how this manifests as clinical symptoms

Watch this video to learn more about how TSLP interacts with mast cells in asthma, contributing to airway hyperresponsiveness

Watch this video to learn more about damage to the airway epithelium in asthma and the central role of epithelial cytokines in driving inflammatory responses

Download this slide deck to access 3D image stills of the asthma mechanisms of disease video and learn more about the central role of the epithelium in disease pathogenesis

Watch this video to explore the key pathological mechanisms that underpin asthma, and the central role of the airway epithelium and epithelial cytokines in driving disease

Watch this video to see Professor Ian Pavord present a patient case study of allergic asthma with allergic triggers, and learn more about how epithelial cytokines are involved in driving this type of asthma

Watch Professor Christopher Brightling discuss the role of epithelial cytokines in the various inflammatory pathways that underpin asthma and its different phenotypes

Explore this slide content to learn more about epithelial cytokines in the context of the clinical features of asthma, including the impact on everyday clinical practice and patient care

Download this one-page summary infographic detailing the substantial clinical and economic burden associated with severe asthma, despite available treatments

Download this one-page summary infographic to learn more about the consequences of sub-optimal disease control in severe asthma

Explore this slide content to learn more about the healthcare burden of severe asthma and unmet need that exists for patients

Download this one-page summary infographic to learn more about the central role of the airway epithelium in inflammation and asthma

Download this one-page summary infographic to learn more about the complexity of severe asthma, specifically the concurrent overlapping inflammatory pathways that may present in patients with asthma

Download this one-page summary schematic detailing the three key inflammatory pathways that underpin asthma pathogenesis

Download this one-page summary infographic to explore the sources, targets and effects of the three key epithelial cytokines involved in asthma disease pathogenesis

Explore this slide content to learn more about the central role of the airway epithelium in asthma and how external triggers initiate the inflammatory mechanisms that underpin the disease